JANUMET XR is a prescription medicine that contains 2 prescription diabetes medicines, sitagliptin
(the medicine in JANUVIA®) and extended-release metformin HCI.

Dosing may be different for different people. Make sure you take the medicine exactly as your doctor tells you to.

  • It is recommended that JANUMET XR be taken once daily with food, preferably in the evening, to lower
    the risk of an upset stomach
  • Swallow tablets of JANUMET XR whole. Never crush, split, or chew the tablets
  • You may see something that looks like the JANUMET XR tablet in your stool (bowel movement). If you
    see tablets in your stool several times, talk to your doctor
  • Continue to take JANUMET XR for as long as your doctor advises
  • It's important not to miss doses of your type 2 diabetes medicines

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines,
vitamins, and herbal supplements. JANUMET XR may affect how well other drugs work and some drugs can
affect how well JANUMET XR works.

Taking JANUMET® XR (sitagliptin and metformin HCl extended-release) tablets can be an important step toward getting blood sugar under control. If you have type 2 diabetes, talk to your doctor to find out whether JANUMET XR is right for you. Along with taking JANUMET XR, follow your doctor's recommendations about eating healthy, staying active, and losing weight.

If you have any questions about how to take JANUMET XR, make sure you ask your health care professional
right away.

Before you take JANUMET XR, tell your doctor if you:

  • have or have had inflammation of your pancreas (pancreatitis).
  • have severe kidney problems.
  • have liver problems.
  • have heart problems, including congestive heart failure.
  • drink alcohol very often, or drink a lot of alcohol in short-term “binge” drinking.
  • are going to get an injection of dye or contrast agents for an x-ray procedure; JANUMET XR may need
    to be stopped for a short time. Talk to your doctor about when you should stop JANUMET XR and
    when you should start JANUMET XR again.
  • have any other medical conditions.
  • are pregnant or plan to become pregnant. It is not known if JANUMET XR will harm your unborn baby. If
    you are pregnant, talk with your doctor about the best way to control your blood sugar while you are
  • are breast-feeding or plan to breast-feed. It is not known if JANUMET XR will pass into your breast milk.
    Talk with your doctor about the best way to feed your baby if you are taking JANUMET XR.

Click the links below for more important information you should know about JANUMET XR.


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