What Is Type 2 Diabetes?

Type 2 diabetes is a condition in which:

  1. Your pancreas does not make enough insulin
  2. The insulin that your body makes does not work as well as it should
  3. Your liver also makes too much sugar. When sugar (glucose) builds up in the blood, over time it can lead to serious medical problems.

One of the goals of treating type 2 diabetes is to lower blood sugar, but you should also be careful of it going too low.

Lowering and controlling blood sugar may help prevent or delay complications of type 2 diabetes, such as:

  • heart problems
  • kidney problems
  • blindness
  • amputation

JANUMET XR and JANUMET are not approved to treat the serious problems that may result from high blood sugar. High blood sugar can be lowered with diet and exercise and with certain medicines when necessary.

JANUMET tablets contain 2 prescription medicines: sitagliptin (JANUVIA®) and metformin. Once-daily prescription JANUMET XR tablets contain sitagliptin (the medicine in JANUVIA®) and extended-release metformin.

JANUMET or JANUMET XR can be used along with diet and exercise to lower blood sugar in adults with type 2 diabetes.

JANUMET or JANUMET XR should not be used in patients with type 1 diabetes or with diabetic ketoacidosis (increased ketones in the blood or urine). If you have had pancreatitis (inflammation of the pancreas), it is not known if you have a higher chance of getting it while taking JANUMET or JANUMET XR.


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